New virus treatment  could  be major breakthrough

The preliminary results of a UK clinical trial suggest a new treatment for Covid-19 reduces the number of patients needing intensive care, according to the UK company that developed it.

The treatment from Southampton-based biotech Synairgen uses a protein called interferon beta which the body produces when it gets a viral infection.

The protein is inhaled directly into the lungs of patients with coronavirus, using a nebuliser, in the hope that it will stimulate an immune response.

The initial findings suggest the treatment cut the odds of a Covid-19 patient in hospital developing severe disease – such as requiring ventilation – by 79%.

Patients were two to three times more likely to recover to the point where everyday activities were not compromised by their illness, Synairgen claims.

It said the trial also indicated “very significant” reductions in breathlessness among patients who received the treatment.

In addition, the average time patients spent in hospital is said to have been reduced by a third, for those receiving the new drug – down from an average of nine days to six days.

The double-blind trial involved 101 volunteers who had been admitted for treatment at nine UK hospitals for Covid-19 infections.

Half of the participants were given the drug, the other half got a placebo – an inactive substance.

Unconfirmed results
Stock market rules mean Synairgen is obliged to report the preliminary results of the trial.

The results have not been published in a peer-reviewed journal, nor has the full data been made available so the claims made for the treatment cannot be confirmed.

 if the results are as the company says, it will be a very important step forward in the treatment of coronavirus infections.

The scientist in charge of the trial, Tom Wilkinson, says if the results are confirmed in larger studies the new treatment will be “a game-changer”.

The trial was relatively small but the signal that the treatment benefits patients were unusually strong, he says.

“We couldn’t have expected much better results than these,” Synairgen chief executive Richard Marsden told the BBC.

He described the results as “a major breakthrough in the treatment of hospitalized Covid-19 patients”.

The scientist in charge of the trial, Tom Wilkinson, says if the results are confirmed in larger studies the new treatment will be “a game changer”.

The trial was relatively small but the signal that the treatment benefits patients was unusually strong, he says.

“We couldn’t have expected much better results than these,” Synairgen chief executive Richard Marsden told the BBC.

He described the results as “a major breakthrough in the treatment of hospitalised Covid-19 patients”.